profesora de la Escuela de odontología de la Universidad del Valle (Cali, Colombia). RESUMEN. El objetivo de esta laserterapia y los marcadores bioquímicos Esteves-Oliveira M, Aranha AC, Ramalho. KM, Simões A. Aranha, F. L. Bioquímica odontológica. São Paulo: Sarvier. 2. ed. p, Berne, R. M.; Levy, M. N. Physiology. St Louis: Mosby. ; Ten Cate AR. Histologia bucal, desenvolvimento, estrutura e função. 5a ed. Rio de Janeiro: Guanabara Koogan; 3. Aranha FL. Bioquímica odontológica.


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Clinical signs arise on the feet, on the legs, and later on the hands.

As the disease progresses, the person may have other clinical signs, such as scoliosis, pes cavus, and tremor of the hands bioquimica odontologica aranha 12 ].

Reports of respiratory dysfunction such as diaphragmatic weakness have been described [ 13 — 16 ].

Sensory hearing loss can also occur [ 1718 ], paresis bioquimica odontologica aranha the vocal cords that may be associated with a more severe variant of the disease [ 19 ]. Besides, it was found that this disease can also affect the quality of sleep [ 20 ].

However, to the best our knowledge, studies investigating the influence of this disease in the orofacial region are scarce, with the only case reports investigating the presence of trigeminal neuralgia [ 21 ] and self-reported mastication [ 22 ] in Charcot-Marie-Tooth disease. Although CMT disease is a distal neuropathy preferably, by having a progressive characteristic, the orofacial region may be affected, leading to an impairment of motor bioquimica odontologica aranha which could compromise chewing.

Besides, atrophy and weakness of the intrinsic muscles of the hand, it could also contribute to disability in the oral hygiene of these individuals. So, this study aimed to characterize the condition of oral health and its impact on quality of life as well as to evaluate signs and symptoms of temporomandibular disorders, bruxism, and masticatory bioquimica odontologica aranha in individuals with CMT2 disease from a multigenerational family.

Bioquímica bucal by Robson Pierre on Prezi

Sample and Ethical Consideration The present study was conducted from August to February to evaluate a group of individuals presenting Charcot-Marie-Tooth type 2 disease according to oral health and its impact on quality of life.

It also bioquimica odontologica aranha the signs and symptoms of TMD, bruxism self-reported, and masticatory performance. All these individuals were of the same family and presented the neuropathy transmitted with an autosomal dominant inheritance bioquimica odontologica aranha.

The members of this family live in the city of Tobias Barreto, that is, situated km from Aracaju, Sergipe State, Brazil. The diagnosis of CMT2 was done by a neurologist according to previously described by Neves and Kok [ 2 ].


Additionally, in the present study were included a control group CG which was constituted of individuals living in the same city but without CMT2 disease; this group was too evaluated according to according to oral health and its impact on quality, signs and symptoms of TMD, bioquimica odontologica aranha self-reported, and masticatory performance.

All participants of the study signed a written consent groups and after they were evaluated for the same examiner as explained below. bioquimica odontologica aranha

Oral Health Determination of decayed, missing, and filled teeth Bioquimica odontologica aranha for permanent teeth was done by visual examination according to the criteria set by the World Health Organization [ 23 ]. Salivary Parameters Flow and pH Salivary.

The determination of salivary flow was made directly by reading bioquimica odontologica aranha total volume of stimulated saliva of the subject obtained in five minutes.

For this, the individual chewed continuously for 6 min a gum containing no sugar in its composition.


The bioquimica odontologica aranha saliva produced during the first minutes of stimulation was swallowed or expelled. The basal physiological pH was measured with pH meter immediately after the stimulated saliva was collected to score acid, neutral, or basic [ 24 ].

The determination of the CTS was performed by titration, measuring the volume of lactic acid 0. The indicator is yellow-orange in pH 6.

Close the burette and then read the volume of lactic acid 0. The value of the CTS is the result of the volume of lactic spent multiplied by Individuals were classified according to the risk of caries according to the following groups: This instrument consists of 14 questions divided into seven domains: The questions were answered on a Likert scale with the following scores: Then, the sum of the responses was performed to each question to obtain the total bioquimica odontologica aranha OHIP which bioquimica odontologica aranha vary from 0 to 56 [ 27 ].


Posttraumatic head injury resulting in spasticity disorders and oral injury: Application of prosthodontic skills for tissue protection--a case report. Oral care in the intensive care unit: J Contemp Dent Pract. Dental management bioquimica odontologica aranha oral self- injury in a stroke patient:

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